Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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4,591 – 4,605 of 60,538 results

4,591

Cayman Chemical BAY 87-2243, Purity: ≥98%, CAS: 1227158-85-1, 10 mg

A mitochondrial complex I inhibitor and inducer of ferroptosis; decreases ATP-dependent luciferase reporter activity and ATP levels in H1299luc cells; induces production of ROS, increases α-tocopherol-sensitive lipid peroxidation, and decreases GSH levels in SK-MEL-28 and G361 melanoma cells; reduces tumor weight, HIF-1α levels, and HIF-1α target gene expression in an H460 mouse xenograft model from 0.5-4 mg/kg; reduces tumor growth in the MEXF 276 and MEXF 1732 melanoma PDX mouse models

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4,592

Cayman Chemical WZ4002, Purity: ≥98%, CAS: 1213269-23-8, 100 mg

An irreversible EGFR tyrosine kinase inhibitor that blocks ATP-dependent autophosphorylation of EGFR carrying the T790M mutation as well as an L858R mutation (IC50 = 8 nM); effective in mouse models of lung cancer driven by EGFRT790M

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4,593

AdipoGen Venturicidin A, 33538-71-5, MFCD00036323, 1 mg

MF: C41H67NO11, MW: 750.0, ≥98%, Appearance: White solid. 20-Membered macrolide glycoside. Antibiotic and antifungal agent. Shows antitrypanosomal and antimalarial activity. Potent inhibitor of mitochondrial and bacterial ATP synthase. Inhibitor of F0F1-ATPase. Na+-translocating ATP synthases inhibitor.

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4,594

Medchemexpress LLC Phenyl salicylate | 118-55-8 | MFCD00002213 | 99.9% | 500 G

Phenyl salicylate (PS) exhibits antibacterial activity upon hydrolysis in the small intestine and is frequently employed as a nervous system inhibitor and intestinal preservative. It is utilized in the manufacturing of polymers, lacquers, adhesives, waxes, and polishes, and functions as an ultraviolet filter. This compound also serves as an analgesic, antipyretic, and antiseptic, with additional applications as an antioxidant and food stabilizer.

Exhibits antibacterial activity
Functions as a nervous system inhibitor
Acts as an intestinal preservative
Used in polymer, lacquer, adhesive, wax, and polish manufacturing
Serves as an ultraviolet filter
Offers pain relief as an analgesic
Reduces fever as an antipyretic
Possesses antiseptic properties
Functions as an antioxidant and food stabilizer

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4,595

Cayman Chemical WAY-316606 (hydrochloride), Purity: ≥98%, CAS: 1781835-02-6, 5 mg

An sFRP1 inhibitor (IC50 = 0.5 μM); increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 μM); increases total bone area in a murine calvarial organ culture assay at >0.1 nM

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4,596

Medchemexpress LLC HY-131033 25mg , L-Azidonorleucine (hydrochloride) CAS:1454334-76-9 Purity:>98%

HY-131033 25mg L-Azidonorleucine (hydrochloride) CAS: 1454334-76-9 L-Azidonorleucine hydrochloride, an unnatural amino acid, is A Methionine surrogate. L-Azidonorleucine hydrochloride can be used to label mammalian cell proteins and identify a diverse set of methionyl-tRNA synthetase (MetRS) mutants . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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4,597

Cayman Chemical Arenobufagin, Purity: ≥95%, CAS: 464-74-4, 5 mg

A cardiotonic steroid with anticancer activity; inhibits Na+/K+-ATPase activity in isolated guinea pig ventricular myocytes (IC50 = 290 nM); increases cleavage of PARP, caspase-3, and caspase-9, as well as induces apoptosis in HepG2 hepatocellular carcinoma cells; It inhibits proliferation of HepG2, Hep3B, BEL-7402, and MCF-7 cancer cells (IC50s = 101.9, 39.8, 416.3, and 143.7 nM, respectively), as well as multidrug-resistant HepG2/adm and MCF-7/adr cancer cells (IC50s = 730 and 67.5 nM, respectively); reduces tumor growth, the number and size of lung metastases, and tumor levels of the EMT markers vimentin and β-catenin in a PC3 mouse xenograft model at 1 mg/kg; inhibits VEGF-induced angiogenesis in a Matrigel™ plug assay in mice at 5 and 10 µM/plug

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4,598

Lkt Laboratories Metformin Hydrochloride, ≥98%, 25GR

AMPK activator. CAS: 1115-70-4. Additional sizes available upon request. Ships from Saint Paul, MN.

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4,599

Selleck Chemical LLC ABTS E2917-100MG

ABTS (ABTS diammonium salt AzBTS-(NH4)2) is a substrate for horseradish peroxidase (HRP) conjugate It has commonly been used to assess antioxidant capacity in the Trolox equivalent antioxidant capacity (TEAC) assay

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4,600

Lkt Laboratories Nomilin, ≥98%, 25MG

Triterpene found in species of Citrus; HIV-1 protease and aromatase inhibitor. CAS: 1063-77-0. Additional sizes available upon request. Ships from Saint Paul, MN.

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4,601

Sigma Aldrich Fine Chemicals Biosciences Ciclopirox >=98% (HPLC) | 29342-05-0 | MFCD00599441 | 50MG

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4,602

Medchemexpress LLC SAG (Standard) | 912545-86-9 | 99.6% | 1 MG

This product serves as an analytical standard for a potent Smoothened (Smo) receptor agonist, which functions by activating the Hedgehog signaling pathway and counteracting the inhibitory effects of another compound on Smo.

Functions as an analytical standard.
Potent receptor agonist.
Activates a specific signaling pathway.
Counteracts inhibition of a receptor.
Used in qualitative, quantitative, and methodological research experiments.
Commonly employed in HPLC, GC, and MS applications.

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4,603

TARGETMOL CHEMICALS INC BMS-536924 10MG

Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM modest activity for Mek Fak and Lck with very little activity for Akt1 MAPK1/2. purity: 99%

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4,604

Medchemexpress LLC Carboprost (15(S)-15-Methyl Prostaglandin F2α) | 35700-23-3 | 99.8% | 50 MG

Carboprost is a metabolically stable synthetic analog of prostaglandin F2α. It stimulates uterine contractions and induces abortion. Carboprost is used for postpartum hemorrhage due to uterine atony and for the termination of pregnancy in the second trimester.

Metabolically stable synthetic analog of prostaglandin F2α
Stimulates uterine contractions
Induces abortion
Aids in managing postpartum hemorrhage due to uterine atony
Supports termination of pregnancy in the second trimester

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4,605

Medchemexpress LLC Phenyl sulfate | 937-34-8 | 99.5% | 1 ML

Phenyl sulfate is an orally active gut microbiota-derived metabolite. It induces albuminuria and podocyte damage in podocyte damage in experimental models of diabetes. It can be used as a disease marker in diabetic kidney disease. This product is for research use only and not sold to patients.

Orally active gut microbiota-derived metabolite
Induces albuminuria and podocyte damage in experimental models of diabetes
Functions as a disease marker in diabetic kidney disease
For research use only

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Bioactive Small Molecules

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Medchemexpress LLC Phenyl salicylate | 118-55-8 | MFCD00002213 | 99.9% | 500 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-131033 25mg , L-Azidonorleucine (hydrochloride) CAS:1454334-76-9 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SAG (Standard) | 912545-86-9 | 99.6% | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Carboprost (15(S)-15-Methyl Prostaglandin F2α) | 35700-23-3 | 99.8% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Phenyl sulfate | 937-34-8 | 99.5% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Phenyl salicylate | 118-55-8 | MFCD00002213 | 99.9% | 500 G

Medchemexpress LLC HY-131033 25mg , L-Azidonorleucine (hydrochloride) CAS:1454334-76-9 Purity:>98%

Medchemexpress LLC SAG (Standard) | 912545-86-9 | 99.6% | 1 MG

Medchemexpress LLC Carboprost (15(S)-15-Methyl Prostaglandin F2α) | 35700-23-3 | 99.8% | 50 MG

Medchemexpress LLC Phenyl sulfate | 937-34-8 | 99.5% | 1 ML